Saturday, February 11, 2012

I Wanna Be On The StartupBus?So Freakin? Bad (Video)

Just a little candy to kick off your weekend:?

Looking to get its state on the StartupBus radar, a group?of?Lousiana's innovators?met with founder Elias Bizannes this week for the?Baton Rouge Area Chamber?s February?Innovation Take-Out. After Bizannes' presentation (which he concluded by announcing the first Louisiana StartupBus!), the members of the local tech community unveiled this parody video: "I Wanna Be On The Startup Bus." And yeah, it's pretty cute, guys. Plus, it's always good to see the excitement for building startups outside NY and the Valley.

Source: http://feedproxy.google.com/~r/Techcrunch/~3/-xwJEJkOrYs/

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Friday, February 10, 2012

Journalism & Society: Paul Bomberger: "You Have The Ability To Be ...

DAYS AFTER GRADUATING FROM Temple, Paul Bomberger took a job at his hometown newspaper, the Intelligencer Journal, filling in for a staffer on maternity leave. He was supposed to be at the job for about 9 months. He stayed 15 years.

"You can't beat the newspaper platform for the thrill of a big story," Bomberger said in class yesterday.

At the Intelligencer Journal, he developed a specialty covering business, which eventually landed him in the position of assistant business editor at the Palm Beach Post. He then went to the Sun-Sentinel in Ft. Lauderdale to become the deputy business editor. In 2010, he returned to Pennsylvania to be the editor of Risk & Insurance magazine, a trade publication serving a very engaged, niche audience. He left that position last month and now he's freelancing and consulting.

"I've truly enjoyed doing this," he said, speaking about his career in journalism. "You can make a good living doing this. You'll work hard but you'll be able to pay your bills. And you get a sense that you helped make a difference in your community. You're doing a public service."

His interest in journalism was born here in Philadelphia, where he spent time with his newspaper-loving grandfather. He wrote for his high school newspaper but he also participated in speech and debate groups, learning to write and speak clearly and effectively.

He went to Juniata College for two years but decided he needed to be in a more focused journalism program. So, he came to Temple. He did an internship while he was a student here, and he worked in the Daily News circulation department. He also freelanced for various publications and wrote a few stories for the Temple News.

"When I finished here, I felt like I could compete for a job," he said. "When an editor hands you a story and you can turn it in - and it needs only minimal editing before publishing, you're good to go."

He had a few suggestions for students entering journalism:

? Take advantage of your professors - beyond the classroom.
? Take a wide variety of courses and get involved in a wide variety of stuff while in college.
? Find whatever inspires you, and pursue that.
? "At the end of the day, figure out what you do best," he said. "Where do you shine?"
? The key skills you need to develop are interviewing, researching, writing, figuring out who you need to speak with to get the story, and developing a good bullsh*t detector.

Here are a few other things he said that I found interesting:

? You find stories by reading everything. Then you call people. And you visit them in person. "If you're doing a story, you want to be eyeball to eyeball with somebody," Bomberger said.
? The key to being a good interviewer is being prepared before speaking to people. Read everything. Know the terminology of the subject your covering. Know the players.
? Get anecdotes that you can use to build excitement in your stories.
? Being a good writer means having the ability to get the essential facts to people in a clear, coherent fashion that is easy and enjoyable to read.
? You need to have authority in the story. You understand everything. If you don't, you need to continue digging for information and interview more people.
? Magazines offer a lot of space to tell long, analytical stories.
? Recongnize who your audience is when you write. Trade magazines, for instance, speak to a very knowledgable readership.

"You have the ability to be whatever you want to be," Bomberger said. "Take risks. Go after it. Be accurate, balanced and maintain your integrity. Follow your principles and do not compromise."

What stood out for you?

Source: http://j1111.blogspot.com/2012/02/paul-bomberger-you-have-ability-to-be.html

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Thursday, February 9, 2012

Low dopamine levels during withdrawal promote relapse to smoking

Wednesday, February 8, 2012

Mark Twain said, "Giving up smoking is the easiest thing in the world. I know because I've done it thousands of times." Many smokers would agree that it's difficult to stay away from cigarettes. A new study in Biological Psychiatry this month now suggests that low dopamine levels that occur as a result of withdrawal from smoking actually promote the relapse to smoking.

Dopamine is a brain chemical messenger that is critically important in reward and motivation. Some research suggests that one of its central roles is to send a signal to the brain to 'seek something enjoyable'. Indeed, dopamine is released during many rewarding experiences, including taking drugs, smoking, having sex, and eating food.

This signal seems to depend on the dopamine which is released in response to environmental cues, called phasic release, as opposed to the tonic seepage of small amounts of dopamine from nerve cells. The tonic release of dopamine is implicated in helping the dopamine system set the level of its reactivity to inputs.

Since dopamine is released by smoking, it makes sense that dopamine levels become abnormal when a smoker chooses to stop smoking. Researchers from Baylor College of Medicine in Texas undertook their study to characterize these changes.

They studied mice that were administered nicotine, the active constituent of cigarettes, for several weeks. The researchers then withheld the nicotine and measured the subsequent alterations in dopamine signaling during the withdrawal period.

They reported that withdrawal from nicotine produced a deficit in dopamine in which the basal dopamine concentration and tonic dopamine signals were disproportionately lower than the phasic dopamine signals. Re-exposure to nicotine reversed the hypodopaminergic state.

"This study is an elegant example of yet another way that addiction 'hijacks' the reward system. The phasic release of dopamine triggers us to seek things that, in theory, help us to adapt to our environment," commented Dr. John Krystal, editor of Biological Psychiatry. "However, in addiction the phasic release of dopamine is heightened and it triggers the pursuit of abused substances. This disturbance of dopamine function would, conceivably, make it that much harder to avoid seeking drugs of abuse."

According to the authors, these findings indicate that medications which could help elevate tonic dopamine levels during withdrawal may be successful treatment strategies for nicotine-dependent individuals attempting to quit smoking. Theoretically, such a treatment could help normalize any fluctuating dopamine levels from the sudden lack of nicotine, and also lessen the dopamine-influenced urges to seek out the nicotine, leading to relapse.

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The article is "Withdrawal from Chronic Nicotine Exposure Alters Dopamine Signaling Dynamics in the Nucleus Accumbens" by Lifen Zhang, Yu Dong, William M. Doyon, and John A. Dani (doi:10.1016/j.biopsych.2011.07.024). The article appears in Biological Psychiatry, Volume 71, Issue 3 (February 1, 2012), published by Elsevier.

Elsevier: http://www.elsevier.com

Thanks to Elsevier for this article.

This press release was posted to serve as a topic for discussion. Please comment below. We try our best to only post press releases that are associated with peer reviewed scientific literature. Critical discussions of the research are appreciated. If you need help finding a link to the original article, please contact us on twitter or via e-mail.

This press release has been viewed 78 time(s).

Source: http://www.labspaces.net/117466/Low_dopamine_levels_during_withdrawal_promote_relapse_to_smoking

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Getting caffeine fix as easy as taking deep breath

(AP) ? Move over, coffee and Red Bull. A Harvard professor thinks the next big thing will be people inhaling their caffeine from a lipstick-sized tube. Critics say the novel product is not without its risks.

The product, called AeroShot, went on the market late last month in Massachusetts and New York, and is also available in France. A single unit costs $2.99 at convenience, mom-and-pop, liquor and online stores.

Biomedical engineering professor David Edwards said AeroShot is safe and does not contain common additives, like taurine, used to amplify the caffeine effect in common energy drinks. Each grey-and-yellow plastic canister contains 100 milligrams of caffeine powder, about the amount in a large cup of coffee, plus B vitamins.

But Democratic U.S. Senator Charles Schumer of New York wants the U.S. Food and Drug Administration to review AeroShot, saying he fears it will be used as a club drug so that young people can drink until they drop. Schumer's national press secretary did not immediately respond to calls for comment.

FDA spokeswoman Siobhan DeLancey declined to comment, saying the agency will respond directly to Schumer on the matter.

Edwards said Schumer's comments are understandable in the context of developments over the last few years, when students looking for a quick and cheap buzz began consuming caffeine-packed alcoholic drinks they dubbed "blackout in a can" because of their potency. But he said AeroShot is not targeting anyone under 18 and it safely delivers caffeine into the mouth, just like coffee.

"Even with coffee ? if you look at the reaction in Europe to coffee when it first appeared ? there was quite a bit of hysteria," he said. "So anything new, there's always some knee-jerk reaction that makes us believe 'Well, maybe it's not safe.'"

Once a user shoots a puff of calorie-free AeroShot into his or her mouth, the lemon-lime powder begins dissolving almost instantly. Each single-use container has up to six puffs.

"The act of putting it in your mouth is the act of breathing ? so it's sort of surprising and often people the first time they take the AeroShot, they laugh ... that it's kind of a funny way of putting food in your mouth," said Edwards, who also came up with a breathable chocolate product a few years back.

Dr. Lisa Ganjhu, a gastroenterologist and internal medicine doctor at New York-based St. Luke's-Roosevelt Hospital, said people need to be aware of how much caffeine they are ingesting.

"You want those 10 cups of coffee, it will probably take you a couple hours to get through all that coffee with all that volume that you are drinking," Ganjhu said. "With these inhale caffeine canisters you can get that in 10 of those little canisters ? so you just puff away and you could be getting all of that within the hour."

Even the product packaging warns people not to consume more than three AeroShots per day.

Northeastern University students who sampled the product recently gave it mixed reviews.

"This tastes really good and I think it rocks," student Zack Huang said after puffing onto a free sample before rushing to join a group of friends who were walking away from campus.

Still, one student was not happy with the taste, echoing sentiment expressed online by some consumers.

People elsewhere vowed they would never give up their morning coffee.

"I want to brew it, I want to stir it and I want to drink it slowly as I absorb the caffeine," said longtime coffee fan Mark Alexander.

The makers of AeroShot appear to be aware of that sentiment, declaring that the product isn't about switching away from coffee, but rather making it easier for people with active lifestyles to get their caffeine fix.

"AeroShot can be used in a variety of settings inconvenient for liquids, such as when you study in the library, board an airplane or get into the car for a long drive," they say in the section dedicated to frequently asked questions on their website. "It's easy to take AeroShot with you when you go biking, skiing, curling, or any other activity that consumes energy."

AeroShot, manufactured in France and the flagship product of Cambridge-based Breathable Foods Inc., is the product of a conversation that Edwards had with celebrity French chef Thierry Marks over lunch in the summer of 2007.

"We were discussing what interesting culinary art experiments we might do together and I had the idea that we might breathe foods since I've done a lot of work over the last 10 or 15 years on medical aerosols," Edwards said.

The first venture Edwards worked on with Harvard students was the breathable chocolate, called Le Whif. Now he's preparing to promote a product called Le Whaf, which involves putting food and drinks in futuristic-looking glass bowls and turning them into low-calorie clouds of flavor.

___

Rodrique Ngowi can be reached at www.twitter.com/ngowi

Associated Press

Source: http://hosted2.ap.org/APDEFAULT/386c25518f464186bf7a2ac026580ce7/Article_2012-02-08-Inhalable%20Caffeine/id-0fb5f0af32c8434ba20d98a668602005

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Wednesday, February 8, 2012

Workplace Cleaning Business Marketing Approaches ? Apple TV ...

The most efficient way of gaining consumers in the workplace cleaning company is through referrals as this technique involves completely no customer acquisition costs. It is difficult to stay off word of mouth marketing by yourself however. For this cause it is essential that you have standard promotion campaigns in area to acquire clients as you are beginning out so that you retain a steady stream of new inquiries coming in about time.

In the write-up we appear at a amount of workplace cleaning company promotion approaches and we set out some ideas on organizing campaigns.

Huge Budget Possibilities

With workplace cleaning currently being a localized market you only want to target nearby individuals with your promotion campaigns. Huge media options like tv are generally out of the question for independent operators. Nearby radio and newspaper promotion are some of the large finances options that you could attempt but they are typically out of the finances range that new marketplace entrants can afford.

Your Company Web site

The moment you have a great internet site up there are so several techniques to encourage it on the internet. Nonetheless, for this write-up I will stick mostly with offline promotion approaches.

Auto Promoting

Really dont neglect this one as it delivers a way of finding some great publicity in your neighborhood for free of charge. The moment you pay out for the first expense of possessing magnetic indications created or a automobile wrap utilized to your company automobile you have several many years of free of charge publicity to appear ahead to.

Nearby Company Directories

An advertisement in the Yellow Pages can be pricey but it is frequently the initial area that individuals appear when they want a cleaning services.

Think Exterior the Box

Borrow ideas from other services market corporations in your place. Get with each other with some similar corporations and evaluate ideas. Search at how you could operate with each other to do joint promotion promotions in a way that permits you to split the costs.

You ought to test out several various promotion approaches and you ought to always attempt to track your results to isolate the approaches that are price efficient and bringing in results.

A great way to start finding ideas is to appear at what your competitors are carrying out. If they have been all around for a number of many years then it is possible that they have examined several promotion approaches and are sticking with the winners only.

Constantly retain in mind that you may have to run an advert about a prolonged time period of time for it to be efficient. If individuals see it about and about once more you will sink into their unconscious mind and they will remember your advert when they want an workplace cleaning company.

Profitable promotion ought to be the foundation of your workplace cleaning company marketing efforts. Promoting, when done appropriately will make sure that your phone is always ringing and that you have the quantity of leads that you want to be signing up a standard stream of new consumers.

Business Leads

Source: http://appletvrentals.com/index.php/2012/02/workplace-cleaning-business-marketing-approaches-2/

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How Cheap Travel Insurance Keeps You Covered throughout Your ...

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Source: http://www.businesstraveltours.com/how-cheap-travel-insurance-keeps-you-covered-throughout-your-holiday-trip.html

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Tuesday, February 7, 2012

Paul Harris Fulfills Destiny, Will Try Out At NFL Combine

Photo

When it comes to Paul Harris, I swear there's always been something in the universe working against him making it to the NBA.

Whether it's an injury or a personal matter or whatever, his pro basketball career always seemed to derail itself just as it was starting to get going.

Maybe it's because, ultimately, he was supposed to be a tight end in the National Football League.

Harris is going to attempt to prove correct the hundreds of Syracuse Orange fans who said over the years that Harris should have played football instead of basketball by trying to do just that.


Harris went to add that "...if someone ask me what sport I play I would have to say football WOW I don't know if I can do it I LOVE BASKETBALL to much!!"

Harris was waived by the Maine Red Claws for the third time a few weeks back and I suppose it can't hurt for the 6'4", 193 pound.

How he ended up getting an invite to the NFL Combine, I suppose we'll find out. Maybe Paul is going to pull a Willie Mays Hayes and just show up. Regardless, I'm kinda excited to see what will happen.

Of course, if he ends up being a success, we'll curse him all over for not playing while at SU.

Source: http://www.nunesmagician.com/2012/2/6/2773990/paul-harris-nfl-combine-syracuse-orange-maine

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